The synod of the CRC represents the churches of all the classes. Synod meets annually in June with 192 delegates: one minister, one elder, one deacon, and one other officebearer from each classis. The tasks of synod include responsibility for creeds, the Church Order, liturgical forms, hymnals, principles of worship, and moral/ethical positions.

Synod also provides general oversight for the ministries undertaken jointly by CRC churches. These include educational institutions, a broadcast ministry, world and domestic mission agencies, a world relief agency and a publication ministry, as well as pastoral ministries such as chaplaincy, disability concerns, pastor-church relations, race relations, safe church, and social justice and world hunger concerns.